adenosine deaminase

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Related to adenosine deaminase: Adenosine deaminase deficiency
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Noun1.adenosine deaminase - an enzyme found in mammals that can catalyze the deamination of adenosine into inosine and ammonia; "ADA deficiency can lead to one form of severe combined immunodeficiency disease"; "the gene encoding ADA was one of the earlier human genes to be isolated and cloned for study"
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
References in periodicals archive ?
Biologic material: C57BL/6J adenosine deaminase (ADA)-deficient mice.
The reaction mixture contained 80 [micro]mol/L SAH, 2 kU/L adenosine deaminase, 0.
Adenosine Deaminase: In tubercular pleural effusion pleural fluid Adenosine deaminase level (ADA) has got a good diagnostic index after excluding other causes of raised ADA levels.
Expression of ectoadenosine deaminase and CD26 in human T cells triggered by the TCR-CD3 complex: Possible role of adenosine deaminase as costimulatory molecule.
Children afflicted with this disorder lack the enzyme adenosine deaminase, a problem that results in destruction of white cells that help the body fight infection.
This study made an attempt to investigate the role of Adenosine deaminase activity and lymphocytic/neutrophil ratio in combination to diagnosis of tubercular pleural effusion.
Adenosine deaminase level of less than 40 U/L practically excludes the tubercular aetiology in exudative pleural effusion cases and thus may be useful in differentiating tuberculous aetiology from others in exudative pleural effusion.
Adenosine deaminase (ADA) values of pleural fluid between the two groups were not significantly different (P = 0.
3,16) Elevated pleural fluid adenosine deaminase (>40 U/L) is sensitive, albeit nonspecific, for the presence of TB microorganisms.
5) Enzyme replacement therapy is available for adenosine deaminase deficiency-SCID as well as gene therapy, in Europe.

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