This new study used genome sequencing and found mutations in one specific gene related to obesity: adenylate
cyclase 3 (ADCY3).
The sedative effect of dexmedetomidine is probably mediated by the activation of presynaptic a-2 adrenoreceptors in the locus coeruleus, leading to inhibition of release of norepinephrine, along with it, inhibition of adenylate
cyclase may lead to hypnotic response.
Salbutamol elevates intracellular concentration of cyclic AMP (cAMP) by activating adenylate
i] class tend to be inhibitory guanosine triphosphate (GTP)-binding regulators of adenylate
cyclase ("i" indicates inhibitory), while members of the [G[alpha].
The viability of the cell of organ and tissue is maintained when the adenylate
energy charge of the cell is equal to the value of one (Atkinson, 1968) (Figure 1).
6] It is also involved in several processes including hormone receptor binding; gating of calcium channels; transmembrane ion flux and regulation of adenylate
cyclase; muscle contraction; neuronal activity; control of vasomotor tone; cardiac excitability; and neurotransmitter release.
Normalization of the adenylate
kinase (AK)-based cytotoxicity assay
Cloning, tissue distribution and effects of food deprivation on pituitary adenylate
cyclase activating polypeptide (PACAP) / PACAP-related peptide(PRP) and preprosomatostatin 1 (PPSS 1) in Atlantic cod (Gadus morhua).
MC1R is activated by alpha-melanin stimulating hormone in melanocytes, and then stimulates the G[alpha]s to produce cAMP in melanocytes by the function of adenylate
cyclase, resulting in eumelanin production (Robbins et al.
7) Resistance to aminoglycosides is related to the overexpression of efflux pumps or production of modified enzymes of phosphorylate, acetylate, or adenylate
A gene encoding adenylate
cyclase tac1, was isolated from T.
To investigate the mechanism underlying the endotheliumi-ndependent relaxation, inhibitors of cyclic adenylate
cyclase (SQ 22536, 10 [micro]M) and soluble guanylate cyclase (ODQ 10 [micro]M) were used.