14]C]DDE binding was confined to zona fasciculata, while zona glomerulosa, zona reticularis, and the adrenal medulla
were devoid of bound radioactivity (above the background levels).
In contrast, in the adult, the mature adrenal medulla
replaces the involuted organ(s) of Zuckerkandl to form the largest collection of paraganglionic tissue.
TH is expressed mainly in specific brain areas and in the adrenal medulla
In these cases, the differential diagnosis has to be made with alveolar sarcoma, fibrous malignant histiocytoma, alveolar rhabdomyosarcoma, liposarcoma, variant of malignant melanoma, and some large carcinomatous metastases (especially from kidney, thyroid, adrenal medulla
, and liver).
1) Most such tumors arise from the adrenal medulla
, while the term paraganglioma is used for this same tumor which occurs about 15% of the time in other anatomic sites.
While the primary goal of the project is to characterize the molecular mechanisms underlying acute O2 sensing by arterial chemoreceptors (carotid body CB- and adrenal medulla
AM-), we will also extend our study to other organs (e.
The sites of origin of ganglioneuroblastoma include adrenal medulla
, extra-adrenal retroperitoneum, posterior mediastinum, the neck, and pelvis.
Phaeochromocytomas are neuro-endocrine catecholamine-secreting tumours that arise from chromaffin cells of the adrenal medulla
or sympathetic paraganglia.
PCCs are typically found in the adrenal medulla
, accounting for 80%-85% of cases.
Pheochromocytomas are rare catecholamine producing neuroendocrine tumors typically located in the adrenal medulla
or along the sympathetic ganglia.
The adrenal medulla
is innervated by the phrenic nerve, the vagus nerve, and the sympathetic trunk.
For example, adrenaline produced in the adrenal medulla
and released in the early stress response triggers release of the vascular endothelial growth factor by stimulating the growth of blood vessels.