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agglutinin |
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agglutinin [əˈgluːtɪnɪn] n
(Life Sciences & Allied Applications / Biology) a substance, such as an antibody or a lectin, that causes agglutination of cells or bacteria [agglutinate + -in] ThesaurusLegend: Synonyms Related Words Antonyms
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| ? Mentioned in | ? References in periodicals archive | ||
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| 05% Tween (TBS-Tw) with 5% bovine serum
albumin for 2 hours and then with Helix pomatia agglutinin (HPA)
biotinylated lectin, which recognizes Nacetyl-D-galactosamine (GalNAc),
a typical carbohydrate in O-glycans. Patients may also present with
lymphadenopathy, splenomegaly, hyperviscosity syndrome,
cryoglobulinemia, peripheral neuropathy, cold agglutinin hemolysis,
autoimmune thrombocytopenia, von Willebrand's disease and, in rare
cases, amyloidosis. The technology utilizes AIST's proprietary carbohydrate ligand
to detect even 15ng of ricin, 1/10,000 the amount of lethal dose, in
just 10 minutes, and, with combined use of three synthesized sugar
derivatives fixed on a toxin sensor chip, identifies RCA60 and RCA120,
similarly structured recin agglutinin. |
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