Glycyrrhetic acid (a metabolic substance and aglycon
of glycyrrhizin) induces apoptosis in human hepatoma, promyelotic leukemia and stomach cancer cells.
The main components of these compounds are glycosides that consist of a glycon part and an aglycon
part connected through a glycosidic bond that can be created by a glycosylation reaction.
Among secondary metabolites, diterpene glycosides of Stevia rebaudiana Bertoni plants with steviol (13-hydroxy-ent-kaur-16-en-19-oic acid) as aglycon
is of particular interest .
Several oligosaccharides have been isolated from plants which contain L-rhamnose with aglycon
moiety at C-4 position  e.
Quercetin, flavonol aglycon
, was not registered in the fruit under analysis, possibly due to the fact that it is found in nature as glycosidic bond (BEHLING et al.
Bee pollens contain mainly flavonol glycosides, usually quercetin, kaempferol, herbacetin, or isorhamnetin derivatives, and some also contained aglycon
types which were generally not represented as glycosides, e.
A team at Yale, led by chemist Seth Herzon, managed to create the chemical called lomaiviticin aglycon
, opening up new avenues of exploration into novel chemotherapies that could target cancer stem cells, thought to be the precursors to tumors in a number of different cancers including ovarian, brain, lung, prostate and leukemia.
Ltd 8C34 Aconitum UAB 8NE12 Acyfabrik SA 8B62 Adelphi Healthcare Packaging 8C71 Aeropump, GmbH 8F84 Agenda 1 Analytical Services Limited 8NE11 Agenolab GMBH & Co KG 8D27 Aglycon
8E84 Alfa Wassermann 8B49 Algorithme Pharma Inc.
Quercetin itself is an aglycon
or aglucone that does not possess a carbohydrate moiety in its structure.
In the case of astilbin, however, the sugar attached to aglycon
is rhamnose, which is likely difficult to hydrolyze since there have been no reports on the existence of rhamnosidase in rat gut.
Quercetin, a flavonol aglycon
, is a more potent antiradical substance than quercitrin, which is a quercetin monosaccharide derivative with a [C.
I learned that the ginsenosides that contain no sugar, called aglycon
sapogenins, are the most effective ones for treating cancer.