agranulocytosis


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Related to agranulocytosis: neuroleptic malignant syndrome

a·gran·u·lo·cy·to·sis

 (ā-grăn′yə-lō-sī-tō′sĭs)
n.
An acute condition characterized by a marked decrease in circulating granulocytes, especially neutrophils, and often leading to infection. It is usually drug-induced or caused by exposure to radiation or toxic chemicals.

agranulocytosis

(əˌɡrænjʊləʊsaɪˈtəʊsɪs)
n
(Pathology) a serious and sometimes fatal illness characterized by a marked reduction of leucocytes, usually caused by hypersensitivity to certain drugs

a•gran•u•lo•cy•to•sis

(əˌgræn yə loʊ saɪˈtoʊ sɪs)

n.
an acute blood disorder characterized by a loss of circulating granulocytes, leading to fever and ulcerations of the mucous membranes.
[1925–30]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.agranulocytosis - an acute blood disorder (often caused by radiation or drug therapy) characterized by severe reduction in granulocytes
blood disease, blood disorder - a disease or disorder of the blood
Translations

a·gran·u·lo·cy·to·sis

n. agranulocitosis, condición aguda causada por la disminución excesiva de leucocitos en la sangre.
References in periodicals archive ?
1,2,4) Severe adverse reactions associated with levamisole include agranulocytosis, vascular occlusive disease, and thrombotic vasculopathy with or without vasculitis.
Differences in fever duration between the agranulocytosis and nonagranulocytosis groups were significant (6.
permanent or life-threatening adverse effects, such as tardive dyskinesia or agranulocytosis
As there was no organomegaly and no cellular atypia, and since he was on antibiotics for the ulcer, the diagnosis offered was drug-induced agranulocytosis.
3) Pre-marketing clinical trials of olanzapine did not demonstrate any evidence of agranulocytosis or haemotoxicity.
The study concluded that the incidence of agranulocytosis is too low to consider it a public health problem, and that, due to the small number of cases, associations cannot be analyzed.
DDS causes common adverse effects like hemolytic anemia in G6PD deficient patients, methemoglobinemia, agranulocytosis, hepatitis, peripheral neuropathy, insomnia and psychosis.
International agranulocytosis and aplastic anemia study; incidence of aplastic anemia, the relevance of diagnostic criteria.
Hematologic side effects, such as agranulocytosis and neutropenia, necessitate white blood cell (WBC) monitoring; this has been a long-standing barrier to the use of clozapine.
Drug-drug interactions for methimazole include increased bone marrow depression when combined with antineoplastics, decreased antithyroid effect in combination with amiodarone (Cordarone[R]), and increased risk for agranulocytosis with phenothiazines.
Other concerns regarding the use of clozapine in PD patients are anticholinergic effects, metabolic disturbances, and the risk of agranulocytosis.
Neutropenia and agranulocytosis in patients receiving clozapine in the UK and Ireland.