aldose


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Related to aldose: Aldose reductase

al·dose

 (ăl′dōs′, -dōz′)
n.
Any of a class of monosaccharide sugars containing an aldehyde group.

aldose

(ˈældəʊs; -dəʊz)
n
(Elements & Compounds) a sugar that contains the aldehyde group or is a hemiacetal
[C20: from ald(ehyde) + -ose2]

al•dose

(ˈæl doʊs)

n.
a sugar containing the aldehyde group or its equivalent.
[1890–95; ald (ehyde) + -ose2]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.aldose - a monosaccharide sugar that contains the aldehyde group or is hemiacetal
aldohexose - a monosaccharide sugar having six carbon atoms and an aldehyde group
monosaccharide, monosaccharose, simple sugar - a sugar (like sucrose or fructose) that does not hydrolyse to give other sugars; the simplest group of carbohydrates
Translations
References in periodicals archive ?
Purpose: Aldose reductase inhibitors are considered vital therapeutic and preventive agents to address complications caused by hyperglycemia.
monoclonal antibodies, MAbs,) for rheumatoid arthritis (RA) -- Disease modifying anti-rheumatic drugs (DMARDs) -- Non-steroidal anti-inflammatory drugs (NSAIDs), corticosteroids and aldose reductase inhibitors -- Understanding pain pathways and mechanisms of action -- Safety and patient compliance -- Clinical evidence supporting product efficacy
Administration of ascorbic acid and an aldose reductase inhibitor (tolrestat) in diabetes: Effect on urinary albumin excretion.
Erythrocyte aldose reductase activity and sorbitol levels in diabetic retinopathy.
The aldose reductase inhibitory effects of the compounds were determined, and 3-isomangostin was found to be the most active against the enzyme when tested in vitro.
Drugs profile discussed in this report include 2B3-201, adalimumab, ATXUV-1, ATXUV-2, B27-PD, celecoxib, CF-101, Col-Treg, Cytectin, dexamethasone acetate, Dexamethasone Sodium Phosphate-Visulex, Drugs to Inhibit Aldose Reductase for Immunology, Ophthalmology, Infectious Disease, Metabolic and Respiratory Disorders, EBI-028, EC-1496, EC-1669, fluocinolone acetonide, FR-104, gevokizumab, HL-036, IBI-70090, IMD-0354, INV-17, LFG-316, lodamin, NOP-3, NS-2, OX-1001, PA-2612, Peptides to Modulate TCR for Uveitis, plastoquinone decyl triphenylphosphonium bromide, PP-001, PPL-003, Recombinant Enzymes for Uveitis, sarilumab, sirolimus, Small Molecules to Inhibit Kinase for Uveitis and Inflammatory Bowel Disease, Stem Cell Therapy for Autoimmune Diseases, triamcinolone acetonide, V-404.
In contrast, only a few molecules have been developed specifically for NP as a primary indication and these include an aldose reductase inhibitor, a membrane integrity agonist and an opioid kappa receptor agonist.
Taking each in turn, the 50 papers discuss such aspects as acetaldehyde elimination changes in transgenic mice lacking aldehyde dehydrogenase 2 activity, the role of carbonyl metabolizing enzymes in the hepatocyte cytotoxicity of chloral hydrate and tribromoethanol anesthetics, and the search for effective aldose reductase inhibitors.
A COMPARISON OF ALDOSE REDUCTASE ACTIVITY IN WILD-TYPE AND MUTANT STRAINS OF DROSOPHILA MELANOGASTER, Jamila Belgrave, Denise Saunders and Jann P.
Our hypothesis performed exactly as expected, with the experiments showing that aldose reductase is an essential enzyme in the transduction pathways that cause the transcription of the cytokines and chemokines known to act in asthma pathogenesis.
Perhaps the absence of a correlation reflects differing enzyme activities, such as those of aldose reductase, galactokinase, and/or galactose dehydrogenase.
This is due in part to the fact that glucose is metabolized by the polyol pathway, which includes aldose reductase, an enzyme that converts it to a nonmetabolized sugar, sorbitol.