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aldosterone |
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aldosterone [ælˈdɒstəˌrəʊn] n (Life Sciences & Allied Applications / Biochemistry) the principal mineralocorticoid secreted by the adrenal cortex. A synthesized form is used in the treatment of Addison's disease. Formula: C21H27O5 [from ald(ehyde) + -o- + ster(ol) + -one]
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| Current views maintain that the role of
hormones in the salivary glands--particularly aldosterone and
antidiuretic hormone is solely to modify the ionic content of the
saliva. Simultaneously
adrenocorticotropic hormone (ACTH) from the anterior pituitary gland
stimulates the adrenal cortex to release aldosterone and cortisol. Cimetidine, used in the
treatment of peptic ulcers, disrupts the hypothalamo-pituitary-gonadal
axis, and spironolactone, an aldosterone antagonist used for
hypertension, also has an anti-androgenic effect (see Rosen, 1991, for
review). |
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