Also found in: Thesaurus, Medical, Wikipedia.
Related to alendronate: Fosamax, alendronate sodium


A bisphosphonate drug, C4H13NO7P2, that inhibits bone resorption and is used in the form of its sodium salt to treat and prevent osteoporosis in postmenopausal women.

[Probably a(mino) + (buty)l(id)en(e), one of its constituents (butyl + -id(e) + -ene) + (hy)dr(oxy) + (bisphosph)onate.]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.alendronate - a tablet (trade name Fosamax) prescribed to prevent or treat osteoporosis in women after menopausealendronate - a tablet (trade name Fosamax) prescribed to prevent or treat osteoporosis in women after menopause
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease

alendronate, alendronate sodium

(USAN), alendronic acid (INN) n alendronato, alendronato sódico, ácido alendrónico (INN)
References in periodicals archive ?
Contract awarded for alendronate sodium 2,026 igss code and / or alendronate, 70 mg tablet
com/research/3lrgp9/investigation) has announced the addition of the "Investigation Report on China's Alendronate Sodium Market, 2010-2019" report to their offering.
Douglas Bauer of the University of California, San Francisco, and his colleagues looked at data from a trial of about 1,000 postmenopausal women aged 61-86 who had been treated for 4-5 years with alendronate and were randomized to an additional 5 years of alendronate treatment or placebo (JAMA 2014 May 5 [doi: 10.
1) Over 2,000 women were randomized to placebo or alendronate and followed for 36 months.
At 1 year, bone mineral density (BMD) in the spine increased 4% with alendronate (Fosamax), 7% with teriparatide (Forteo), and 11,3% with AMG 785 given at a subcutaneous dose of 210 mg/mo.
Alendronate is commonly used in the treatment of osteoporosis and other bone diseases.
I recently read the interesting case report entitled 'Multiple Fractures Associated with Alendronate Use' published in your journal.
5) Prolonged use of alendronate over 7 to 10 years has shown a continued increase in the bone mineral density without any adverse skeletal events.
A meta-analysis study has demonstrated the efficacy of anti-resorptive agents: raloxifene and etidronate have been shown to reduce the incidence of vertebral fractures, and alendronate and risedronate have been shown to reduce the incidence of both vertebral and hip fractures.
The men were put on continuous weekly alendronate treatment, or intermittent treatment, or no treatment.
The others got alendronate (Fosamax), a drug that preserves bone mass.