alkylating agent

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alkylating agent [ˈælkɪˌleɪtɪŋ]

(Medicine / Pharmacology) any cytotoxic drug containing alkyl groups, such as chlorambucil, that acts by damaging DNA; widely used in chemotherapy

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Noun

alkylating agent - an antineoplastic drug used to treat some forms of cancer

antineoplastic, antineoplastic drug, cancer drug - any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function

chlorambucil, Leukeran - an alkalating agent (trade name Leukeran) used to treat some kinds of cancer

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antineoplastic
antineoplastic drug
busulfan
cancer drug

chlorambucil
cyclophosphamide
drug
Leukeran

TEMODAL (temozolomide) Capsule is an oral, cytotoxic alkylating agent indicated for treating glioblastoma multiforme (GBM).

Schering-Plough's TEMODAL Capsule for Glioblastoma Multiforme Granted ... by JCNN News Summaries

The compounds tested thus far include N-methyl-N'-nitro-nitrosoguanidine (an alkylating agent similar to methyl methane sulfonate) and cadmium (a toxic metal found in tap water).

MIT toxicogenomics research program by Eubanks, Mary / Environmental Health Perspectives

Using these and other factors, the retrospective study of more than 9,000 patients provides strong statistical evidence that approximately half of the secondary bone cancers observed can be blamed on radiation therapy or on chemotherapeutic alkylating agents such as the frequently prescribed cyclophosphamide.

Cancer therapy risks assessed by Weiss, Rick / Science News

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alkyd
alkyd resin
alkyl
alkyl group
alkyl halide
alkyl radical
alkylate
alkylating agent
alkylation
alkylbenzene
alkylbenzenesulfonate
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