alloantibody

(redirected from alloantibodies)
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Related to alloantibodies: alloantigen

al·lo·an·ti·bod·y

 (ăl′ō-ăn′tĭ-bŏd′ē)
n. pl. al·lo·an·ti·bod·ies

alloantibody

(ˈæləʊˌæntɪˌbɒdɪ)
n, pl -bodies
another name for isoantibody
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.alloantibody - an antibody that occurs naturally against foreign tissues from a person of the same species
antibody - any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
References in periodicals archive ?
Immune neutropenia may result from granulocyte-specific autoantibodies, granulocyte-specific alloantibodies, or transfusion-related anti-HLA antibodies.
The latter safety measure should be designed into manual and computerized record-keeping systems to warn of any previous ABO/Rh typing discrepancies, known alloantibodies, previous transfusion reactions, special component requirements, and the availability of reserved autologous or designated units.
These alloantibodies would immediately recognize a transplanted kidney as "foreign" and mount an immune attack against it.
Cheng CK, Wong ML, Lee AW PEG adsorption of autoantibodies and detection of alloantibodies in warm autoimmune hemolytic anemia.
For this study, lymphocytes were tested with a panel of sera containing well-characterized HLA-specific alloantibodies.
All eight recipients became insulin independent, but three did not maintain independence, including two who tested positive for autoantibodies and alloantibodies.
As patients undergo subsequent transfusions, alloantibodies to multiple antigens may develop.
2: Delivery of cards (cassettes) and the reference cell alloantibodies immunological assays and testing compliance without ABO and RhD signs of the donor and the recipient, including the lease of equipment.
This is particularly important when managing patients who receive chronic transfusions, including those with sickle cell disease, thalassemia, or chronic anemia, who are more likely to produce alloantibodies.
Pathophysiologically, the binding of auto- or alloantibodies to factor VIII impedes its clotting activity, with potentially life-threatening complications.
Solid-phase methods, such as enzyme-linked immunosorbent assays (ELISAs) and Luminex (Luminex, Austin, Texas) technology, are increasingly considered to be the methods of choice for characterizing HLA alloantibodies.
CryoLife notes that the effect of reduced alloantibodies on the long-term durability, or long-term resistance to rejection by the patient, of the CryoValve SG has not yet been clinically proven.