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another name for isoantigen


(ˌæl oʊˈæn tɪ dʒən, -ˌdʒɛn)

an antigen present in some but not all individuals of the same species, as those in different human blood groups.
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When the test was performed in the presence of mitogen stimulating lipopolysaccha-rides (LPS), phytohaemagglutinin (PHA), concanavalin A (ConA) and alloantigen, a concentration dependent inhibition of lymphocyte proliferation was observed.
In the skin and GI tissue affected by GVHD, the mechanism of apoptosis is likely similar and caused by alloreactive T lymphocytes targeted to alloantigen on recipient tissue.
In vivo exposure of CD4+CD25+T cells from normal naive mice to alloantigen in a T cell-deficient environment elicits spontaneous expansion of alloantigen-specific CD4+CD25+natural Treg cells, which are able to suppress allograft rejection mediated by subsequently transferred naive T cells, leading to long-term graft tolerance.