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allograft |
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allograft [ˈæləʊˌgrɑːft] n (Medicine) a tissue graft from a donor genetically unrelated to the recipient
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Although allograft rejection is only the second leading cause of mortality for cardiac transplant recipients, immunosuppression is the primary source of morbidity. In 2004, XDx completed the validation phase of the CARGO (Cardiac Allograft Rejection and Gene Expression Observational) study in anticipation of a December 2004 launch of AlloMap molecular expression testing, the company's molecular expression test targeting the post-cardiac transplantation patient management market. of the US Food and Drug Administration (FDA) has granted the Company "Orphan Drug Designation" for its investigational antibodies to interferon-gamma to treat Immunologic Corneal Allograft Rejection. |
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