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allosteric

   Also found in: Medical, Encyclopedia, Wikipedia 0.02 sec.
al·lo·ster·ic  (l-strk)
adj.
Of or involving a change in the shape and activity of an enzyme that results from molecular binding with a regulatory substance at a site other than the enzymatically active one.
allo·steri·cal·ly adv.
al·loster·y (-lst-r) n.
allosteric [ˌæləʊˈstɪərɪk]
adj
(Life Sciences & Allied Applications / Biochemistry) Biochem of, relating to, or designating a function of an enzyme in which the structure and activity of the enzyme are modified by the binding of a metabolic molecule


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Vivalis know-how and proprietary technology are focused in three main areas: licensing the proprietary ebx(TM) chicken embryonic stem cell lines to the pharma and biotech industry, in particular for vaccine and proteins production; contract manufacturing of pre-clinical and clinical batches of viral vaccines and recombinant proteins; and discovery of new anti-viral allosteric modulators through its proprietary 3D-Screen(TM)[3] platform.
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The oxygen binding affinity of natural human hemoglobin is too high when it is free in the blood stream (not contained within erythrocytes) because of a lack of allosteric control.
Macromolecular crystallography and structural biology databases at ... by Gilliland, Gary L. / Journal of Research of the National Institute of Standards and Technology
In its lead inflammation program, Locus has created exquisitely selective p38 inhibitors which bind to p38 at an allosteric site and do not involve the ATP site.
Locus Pharmaceuticals Completes $30.2 Million Financing Round by Business Wire
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