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alpha-adrenoceptor

   Also found in: Encyclopedia 0.03 sec.
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Noun1.alpha-adrenoceptor - receptors postulated to exist on nerve cell membranes of the sympathetic nervous system in order to explain the specificity of certain agents that affect only some sympathetic activities (such as vasoconstriction and relaxation of intestinal muscles and contraction of smooth muscles)
sympathetic nervous system - originates in the thoracic regions of the spinal cord; opposes physiological effects of the parasympathetic: reduces digestive secretions; speeds the heart; contracts blood vessels
receptor - a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response


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The oral decongestants ephedrine, pseudoephedrine, and phenylpropanolamine all have alpha-adrenoceptor agonist activity.
Phentolamine methylate (Regitine) is a competitive, nonspecific alpha-adrenoceptor antagonist that presumably produces smooth muscle relaxation by blocking the (antierectile) postsynaptic [alpha.
Because alpha-adrenoreceptor stimulation produces both vasoconstriction and bronchoconstriction, the pharmacologic reduction of alpha-adrenergic activity via alpha-adrenoceptor antagonists is certainly warranted for patients with pulmonary disease.
 
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