alpha-blocker


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al·pha-block·er

(ăl′fə-blŏk′ər)
n.
A drug that blocks or counteracts the effects of epinephrine and other molecules that stimulate alpha-receptors, leading to various physiological reactions such as vasodilation and a decrease in blood pressure. Also called alpha-adrenergic antagonist, alpha-adrenergic blocker.

alpha-blocker

n
(Pharmacology) any of a class of drugs that prevent the stimulation of alpha adrenoceptors, a type of receptor in the sympathetic nervous system, by adrenaline and noradrenaline and that therefore cause widening of blood vessels: used in the treatment of high blood pressure and prostatic hyperplasia
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.alpha-blocker - any of various drugs that block alpha-adrenergic receptorsalpha-blocker - any of various drugs that block alpha-adrenergic receptors; used in treating benign prostatic hyperplasia; relaxes the muscles of the prostate and bladder
blocking agent, blocker - a class of drugs that inhibit (block) some biological process
Minipress, prazosin - antihypertensive drug (trade name Minipress)
Hytrin, terazosin - antihypertensive drug (trade name Hytrin) used to treat high blood pressure
References in periodicals archive ?
Its combination with an alpha-blocker is effective in improving irritative symptoms, and for select patients with BOO and concomitant detrusor overactivity.
Labetalol is both a selective alpha-blocker and a nonselective beta-blocker that decreases systemic vascular resistance without changing maternal cardiac output.
Our findings do not support this recommendation and should prompt reconsideration of use of an alpha-blocker as the first drug of choice for these patients," he added.
Conventional medical therapy for an enlarged prostate includes alpha-blocker drugs such as Flomax to relax the smooth muscle in the prostate.
perindopril and the alpha-blocker Cardura XL (doxazosin GITS) as add-on
We know that alpha-blocker drugs and Proscar can do the first, and it looks like a combination of the two can do the second," Wilt says.
THE other type of drug used for treating BPH is called an alpha-blocker.
The most studied alpha-blocker has been tamsulosin, although a class effect has been suggested.
The first group consisted of patients receiving diclofenac sodium and an alpha-blocker, the second group of patients received diclofenac sodium and prednisolone, and the third group of patients received diclofenac sodium alone.
Avodart is approved for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate to improve symptoms, reduce the risk of acute urinary retention (AUR), and reduce the risk of the need for BPH-related surgery In combination with the alpha-blocker tamsulosin, Avodart is also approved for the treatment of symptomatic BPH in men with an enlarged prostate.
Oral phentolamine, a nonselective alpha-blocker, has been used successfully for facilitating erections and treating men with ED (32-35).