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alpha-fetoprotein

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.10 sec.
al·pha-fe·to·pro·tein  (lf-ft-prtn, -t-n)
n. Abbr. AFP
An antigen produced in the liver of a fetus that can appear in certain diseases of adults, such as liver cancer. Its level in amniotic fluid can be used in the detection of certain fetal abnormalities, including Down syndrome and spina bifida.

alpha-fetoprotein  (lf-ft-prtn)
An antigen produced in the liver of a fetus that can appear in certain diseases of adults, such as liver cancer. Its level in amniotic fluid can be used in the detection of certain fetal abnormalities, including Down syndrome and spina bifida.


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For HCC biomarkers, alpha-fetoprotein (AFP, 19-fold), plasminogen activator inhibitor-1 (PAI-1, 9-fold), cytokeratin 8 (6-fold), cytokeratin 18 (3-fold) and cytokeratin 19 (11-fold), were dramatically increased in arsenic-induced HCC.
, has completed enrollment for a Phase IIa pilot study in patients with rheumatoid arthritis with its immunomodulatory drug candidate, MM-093, a recombinant version of human alpha-fetoprotein (AFP).
For NSGCTs, tumor markers may be followed; when tumor markers such as human chorionic gonadotropin or alpha-fetoprotein remain elevated, salvage chemotherapy is indicated.
 
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