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macroglobulin
(redirected from alpha2-macroglobulin)

    Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
mac·ro·glob·u·lin  (mkr-glby-ln)
n.
A plasma globulin of high molecular weight.
macroglobulin [ˌmækrəʊˈglɒbjʊlɪn]
n Immunol
1. (Life Sciences & Allied Applications / Biochemistry) an immunoglobulin of unusually high relative molecular mass, observed in the blood in some diseases
2. (Life Sciences & Allied Applications / Biochemistry) Also called immunoglobulin M the normal form of this immunoglobulin
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Alpha2-macroglobulin Alpha2-macroglobulin (AMG) is similar to AAT and most other proteinase inhibitors, except that it is a very large molecule, approximately 750 kD as compared, for example, to antithromin III (only 65 kD).
Plasma proteins as biomarkers: acute phase proteins by Steinert, Don / FOCUS: Journal for Respiratory Care & Sleep Medicine
Chodorowska G, Wojnowska D, Juszkiewicz-Borowiec M: C-reactive protein and alpha2-macroglobulin plasma activity in medium-severe and severe psoriasis.
Investigation of serum leptin levels in psoriatic ... by Gonul, Turkan; Basak, Pinar Yuksel; Kara, Yusuf; Akkaya, Vahide Baysal; Vural, Huseyin / Archives of the Turkish Dermatology and Venerology
They are believed to act by inhibiting fibroblast growth and decreasing alpha2-macroglobulin levels, leading to collagen degradation.
Combined therapy in the treatment of auricular keloids by Oberman, James P. / Ear, Nose and Throat Journal
 
 
 
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