To evaluate its efficacy and tolerability, we performed a retrospective study of consecutive patients with Parkinson's disease (PD) who had received amantadine
either as mono- or combination therapy for a 3-year period.
Evidence of widespread resistance of influenza to amantadine
and rimantadine has prompted calls for restraint in antiviral use in order to preserve the therapeutic value of these adamantanes as well as newer generation agents.
(Symmetrel) has demonstrated a modest benefit on MS fatigue and is much less expensive than modafinil.
The gene sequences of the viruses indicated they were sensitive to the antiviral drugs Tamiflu and amantadine
If taken early, the antiviral agents amantadine
and rimantadine are effective in reducing the severity of influenza A, while zanamivir and oseltamivir are effective in reducing the severity of both influenza A and B.
If you are older or in poor health, your doctor may prescribe amantadine
, oseltamivir, or zanamivir if you have been exposed to the flu virus or if you have flu symptoms.
The M2 blocker amantadine
is widely used and available without a prescription in some countries, including China, note Yi Guan and Honglin then, both of the University of Hong Kong and Shantou University Medical College in China.
Observational studies strongly suggest that amantadine
, rimantadine, and oseltamivir are all effective in reducing spread of influenza during outbreaks in nursing homes (Table).
The World Health Organisation says this year's strain is resistant to cheaper anti- viral drugs amantadine
Medications should be tapered in the order of those with the highest risk-to-benefit ratio: Anticholinergics should be tapered first, followed by selegiline, amantadine
, dopamine agonists, and catechol 0-methyltransferase inhibitors.
Now the appraisal committee will look at a new drug, Tamiflu, which is in the process of being licensed in Europe, and a new formulation of an older drug called amantadine
Rimantadine and amantadine
have been approved for use by adults and children who are 1 year of age and older.