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A theophylline derivative, C16H24N10O4, used as a bronchodilator in the treatment of bronchial asthma, emphysema, and bronchitis.


(Pharmacology) a derivative of theophylline that relaxes smooth muscle and is used mainly to dilate the airways in the treatment of asthma and emphysema
[C20: from amino- + phyllo- + -ine2]


(əˌmi noʊˈfɪl aɪn, -in, ˌæm ə noʊ-)

a theophylline derivative, C16H24N10O4, used chiefly to relieve bronchial spasm in asthma, in the treatment of certain heart conditions, and as a diuretic.
[1955–60; amino- + (theo) phylline]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.aminophylline - a theophylline derivative that is used as a bronchodilator in the treatment of bronchial asthma, emphysema, and bronchitis
bronchodilator - a drug that relaxes and dilates the bronchial passageways and improves the passages of air into the lungs
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References in periodicals archive ?
Compared with traditional theophylline and aminophylline, doxofylline has better efficacy and less toxicity and therefore is worthwhile for spreading in clinical practice.
Colin Whalley, 68, had the chronic lung condition COPD and was being treated at Whiston hospital for breathing problems when he was given a whole day's dosage of aminophylline in just 20 minutes by mistake by nurse Maryann Sanchez.
Secondly, while the majority of recommendations are well formulated and evidence-based, it is surprising to see the use of intravenous aminophylline still promoted: it was removed from international guidelines many years ago and the lack of benefit has been well proven.
Aminophylline (240 mg iv) should be available for immediate use in case an adverse dipyridamole-related event occurs (9).
Aminophylline for methotrexate-induced neurotoxicity.
Intravenous aminophylline and oral theophylline have been used since the 1940s to provide bronchodilation.
Dose-finding study with nimodipine: a selective central nervous system calcium channel blockers on aminophylline induced seizure model in rats.
While still in post-anesthetic care unit (PACU), she felt better and pulmonary auscultation showed basilar crackles and mild cyanosis (pulse oximetry showed a SPO2 of about 80-83%) with moderate dyspnea and orthopnea after receiving furosemide, aminophylline and oxygen through facemask for two hours.
She was treated with nebulised salbutamol, nebulised ipratropium bromide, hydrocortisone IV and an aminophylline intravenous infusion.
13) Randomised controlled trials of intravenous aminophylline in this setting have failed to demonstrate efficacy beyond that induced by accepted other therapies.
The third compound is aminophylline, which is also used as a medicine to treat asthma.