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anaplasia

   Also found in: Medical, Wikipedia 0.07 sec.
an·a·pla·sia  (n-plzh)
n.
Reversion of cells to an immature or a less differentiated form, as occurs in most malignant tumors.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.anaplasia - loss of structural differentiation within a cell or group of cells often with increased capacity for multiplication, as in a malignant tumor
dysplasia - abnormal development (of organs or cells) or an abnormal structure resulting from such growth


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(3) The tumor we describe belongs in this category, although our case is unique in view of our distinguishing findings of the absence of fibrosis and neuronal tissue and the presence of abundant gemistocytes, mild vascular proliferation, perivascular cuffing, mild cellular anaplasia, and mitoses.
Fibromatosis occupies an intermediary position, and microscopic sections contain markedly cellular lesions of mature proliferative fibroblastic tissue, with infrequent mitoses and occasional atypia, but no frank anaplasia.
Nuclear anaplasia can be seen, but mitotic figures are rare.
 
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