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anaplasia

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
an·a·pla·sia  (n-plzh)
n.
Reversion of cells to an immature or a less differentiated form, as occurs in most malignant tumors.

anaplasia [ˌænəˈpleɪsɪə]
n
(Life Sciences & Allied Applications / Biology) reversion of plant or animal cells to a simpler less differentiated form
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.anaplasia - loss of structural differentiation within a cell or group of cells often with increased capacity for multiplication, as in a malignant tumoranaplasia - loss of structural differentiation within a cell or group of cells often with increased capacity for multiplication, as in a malignant tumor
dysplasia - abnormal development (of organs or cells) or an abnormal structure resulting from such growth


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1) The term "dedifferentiated" implies that a portion of cells from the chondrosarcoma have degenerated into a high-grade malignant form that is characterized by pleomorphism, anaplasia, hypercellularity, and increased mitoses.
Based on their cellularity and degree of anaplasia, chondrosarcomas are classified as either low-, medium-, or high-grade tumors.
Nuclear anaplasia can be seen, but mitotic figures are rare.
 
 
 
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