anaplasia


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Related to anaplasia: metaplasia

an·a·pla·sia

 (ăn′ə-plā′zhə)
n.
Reversion of cells to an immature or a less differentiated form, as occurs in most malignant tumors.

anaplasia

(ˌænəˈpleɪsɪə)
n
(Biology) reversion of plant or animal cells to a simpler less differentiated form

an•a•pla•sia

(ˌæn əˈpleɪ ʒə, -ʒi ə)

n.
the loss of structural differentiation within a cell or group of cells.
[1905–10; ana- + -plasia]
an`a•plas′tic (-ˈplæs tɪk) adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.anaplasia - loss of structural differentiation within a cell or group of cells often with increased capacity for multiplication, as in a malignant tumoranaplasia - loss of structural differentiation within a cell or group of cells often with increased capacity for multiplication, as in a malignant tumor
dysplasia - abnormal development (of organs or cells) or an abnormal structure resulting from such growth
Translations

an·a·pla·si·a

n. anaplasia, falta de diferenciación en las células.
References in periodicals archive ?
Grade III (anaplastic) meningiomas are characterized by anaplasia, brain invasion, and [greater than or equal to] 20 mitoses per 10 HPF or are of the rhabdoid or papillary subtypes (Perry et al.
Nevertheless, a few studies have documented minor his top a tho logical differences between AIDS-associated KS and non-HIV associated KS cases [14-16]: lesional cell mitoses and cellular anaplasia are surprisingly more common in HIV-negative patients, whereas KS lesions in HIV-positive patients tend to display more extensive dissecting vessels.
Neoplastic cells showed a high degree of anaplasia, high nucleus-to-cytoplasm ratio, usually one prominent nucleolus, partially condensed chromatin, and high mitotic index.
This behavior is best predicted by the histologic grade, which is determined by 4 factors: mitotic index, degree of cellularity, necrosis when present, and degree of nuclear anaplasia.
We theorize that tumor anaplasia caused malignant myocytes to reexpress CK-MB and cTnT isoforms.
All of these tumor markers in conjunction with lymph-node-positive or lymphnode-negative status combined with the degree of histological anaplasia or with radiological findings of possible metastases define the stage of the disease or the severity of the malignancy.
The benign nature of this lesion was suggested by the lack of any mitotic activity, anaplasia, or dysplasia.
Rhabdomyosarcoma of the urinary bladder in adults: predilection for alveolar morphology with anaplasia and significant morphologic overlap with small cell carcinoma.
Microscopically, the tumor cells were arranged in diffuse compact trabeculae, with variable degrees of anaplasia, and increased mitotic activity in the control group.
One isolated focus of perineural invasion by the epithelial component was noted; there was no lymphovascular invasion, nor any necrosis, anaplasia, or mitosis in the specimen.
1) The term "dedifferentiated" implies that a portion of cells from the chondrosarcoma have degenerated into a high-grade malignant form that is characterized by pleomorphism, anaplasia, hypercellularity, and increased mitoses.
The tumor specimen had extensive areas of calcification, and there were areas of hypercellularity with zones of necrosis; nuclear anaplasia and mitoses were evident.