androgens


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androgens

Male sex hormones produced by the testes and adrenal glands.
Translations
References in periodicals archive ?
Exposure to androgens (male hormones) during brain development alters genes related to autism spectrum disorder (ASD), according to a new study published in Biological Psychiatry.
In men with advanced prostate cancer, growth of cancer cells depends on androgen receptor signaling, which is driven by androgens, such as testosterone.
Washington, March 5 ( ANI ): Researchers including and an Indian origin researcher has said that male hormones, also called androgens, help drive the development of follicles - structures that contain and ultimately release an egg that can be fertilized by a man's sperm.
These include claims for the use of APC-100 to reduce effects of androgens on androgen receptor expressing cancer cells, such as prostate cancer cells.
1] It might suggest that the development and the viability of the gland throughout life require the continued presence of androgens.
Androgens are a group of hormones that play a role in male traits and reproductive activity.
Almost all prostate cancer cells, as well as normal prostate tissues, require androgens for growth and survival.
Testosterone deficiency can result from defects in testicular production of androgens (primary testicular failure), at the hypothalamic-pituitary level (secondary failure), or from combined mechanisms.
In contrast to insulin's role in causing an androgenic shift in metabolism, elevated androgens appear to decrease insulin receptor site sensitivity.
24) Age correlates with a decrease in the ratio of androgens to estrogens in men, suggesting that a physiologic change in hormonal status may contribute to the progression of preneoplastic lesions to adenocarcinoma.
There have also been suggestions regarding the protective role of androgens against high-grade CaP.