anergy

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anergy

(ˈænədʒɪ)
n
1. lack of energy
2. (Physiology) immunol diminution or lack of immunity to an antigen
[from New Latin anergia, from an- + Greek ergon work]
anergic adj

anergy

1. a lack of strength.
2. the failure of the body to respond to an allergen or antigen.
See also: Disease and Illness
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.anergy - reduction or lack of an immune response to a specific antigenanergy - reduction or lack of an immune response to a specific antigen
immunological disorder - a disorder of the immune system
2.anergy - inactivity and lack of energyanergy - inactivity and lack of energy  
inaction, inactiveness, inactivity - the state of being inactive
Translations

an·er·gy

n. anergia.
1. astenia, falta de energía;
2. reducción o falta de respuesta a un antígeno específico.

anergy

n anergia
References in periodicals archive ?
In the setting of immune reconstitution syndrome, there is a reemergence of previously anergic lymphocytes upon viral suppression with HAART (13-16).
The single SA study included in the Cochrane review [12] was an RCT of IPT given twice weekly to TST-negative, HIV-infected adults, all of whom were anergic.
Thus intratumoral Teffs represented functionally active subsets of both Th1 and Th2 which were not anergic but were suppressed by multiple Treg subsets comprising of nTregs, and Tregs secreting TGF[beta]1 and IL10.
The anergic state in sarcoidosis is associated with diminished dendritic cell function.
Anergic condition with manifestation of allergic, auto-allergic and immune-complex pathological processes is also developed in patients.
This protozoa cause a disease with different clinical forms, among them cutaneous, hyperergic, mucocutaneous, and anergic diffuse leishmaniasis (Leon et al.
IL-10 producing T cells suppress immune responses in anergic tuberculosis patients.
Cell extrinsic elements include factors contributing towards immune tolerance; some incriminated in the multistep carcinogenesis of HPV induced cervical cancer are: immunoregulatory enzyme indoleamine 2,3-dioxygenase expressing antigen presenting cells, low numbers of invariant Natural Killer T cells, anergic cytotoxic T lymphocytes, regulatory T cells (Tregs), an immunoregulatory microenvironment comprising of increased ILl0, TGF and reduced IL2; reduced intralesional ratios of effectors (CD4 and CD8) vs.
The advantages of tumor cell-based cancer vaccines must be balanced against two major disadvantages: the potential for autoimmunity and the potential for increasing the anergic status of the T cells due to the lack of functional co stimulatory molecules on tumor cells.
Criteria for enrollment included having a positive or anergic tuberculin skin test response, living within 20 kilometers of the project site, and willingness to be followed.
IL-10 inhibits inflammation by suppressing macrophage CD86 expression leading to anergic T-cells in a schistosomiasis model (Ding et al.