also became more severe, with greater involvement of lips and periorbital tissues and increased pain in lips.
20, 2014 /PRNewswire/ -- CSL Behring today announced it has enrolled the first patient in COMPACT , an international phase III study of a volume-reduced, subcutaneous formulation of C1-esterase inhibitor (C1-INH) concentrate in patients with frequent hereditary angioedema
(HAE) attacks (NCT01912456).
Dyax currently markets KALBITOR([R]) (ecallantide), a specific pKal inhibitor, for treatment of acute hereditary angioedema
(HAE) attacks in patients 16 years of age and older.
SeeNews) - Nov 9, 2012 - US pharma group ViroPharma (NASDAQ:VPHM) has launched sales of a drug for the preventive treatment of hereditary angioedema
SeeNews) - Nov 7, 2012 - Dutch biotechnology firm Pharming Group NV (AMS:PHARM) and US Santarus Inc (NASDAQ:SNTS) unveiled today promising top-line Phase III data for Ruconest (recombinant human C1 esterase inhibitor) in acute hereditary angioedema
is an allergic condition that affects the lips, mouth, tongue, throat, air passages and eyes, causing sudden and sometimes severe swelling.
We report the case of a man who presented at our emergency department (ED) with angioedema
of the lower lip, without urticaria.
Recent laboratory research into the pathophysiology of hereditary angioedema
(HAE) has identified bradykinin as a crucial vasoactive compound in the pathophysiology of attacks (3).
Allergists/immunologists in clinical practice routinely see patients presenting with the primary complaints of itching, hives, angioedema
, and non-pathognomonic rashes that have defied identification and cure during multiple previous encounters with their primary care practitioners, urgent care clinics, emergency rooms, and dermatologists.
Chagas Kde N, Arruk VG, Andrade ME et al: Therapeutic approach of hereditary angioedema
Her paternal grand-mother, great-grandfather, and great-great-grandfather died of asphyxiation due to attacks of angioedema
and swelling of the throat.
is a severe local swelling of the skin, especially around the eyes, lips, nose, tongue, voicebox or hands.