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angiostatin

   Also found in: Wikipedia 0.01 sec.
an·gi·o·stat·in  (nj--sttn)
n.
A naturally occurring protein that is a specific inhibitor of endothelial proliferation and a potent angiogenesis inhibitor. It is under investigation as a potential cancer therapy.
[angio(genesis) + -stat + -in.]
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Angiostatin showed encouraging results in which its ability to shrink primary tumors and inhibit vascularization as well as metastatic colony development were confirmed both through in vitro and animal models.
Generate antiangiogenic peptides by the action of B. polymyxa protease by Emerging Food R&D Report
Angiostatin and endostatin have not lived up to expectations.
War on cancer: New York Times criticizes war on cancer by Moss, Ralph / Townsend Letter
Generation of biologically active angiostatin kringle 1-3 by activated human neutrophils.
Angiogenesis and the tumour microenvironment by Almendro, Vanessa; Gascon, Pere / Advances in Gastrointestinal Cancer
 
 
 
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