It is classified into two major types based on number and functionality of sweat glands: (1) Anhidrotic
or hypohidrotic: Sweat glands are significantly reduced or absent and called as Christ-Siemens-Touraine syndrome.
Furthermore, the anhidrotic
effect of the toxin was noticed after its application in neurologic diseases, and BoNT began to be used in the management of hyperhidrosis in 1994.
skin fissures easily, thereby contributing to the vicious circle of secondary infection and ulceration.
Absent or decreased sweating in patients with anhidrotic
, respectively, hypohydrotic ED is caused by absence of sweat glands.
(hypohidrotic) ectodermal dysplasia is caused by a mutation in a novel transmembrane protein.
Kose O, Tastan HB, Deveci S, Gur AR: Anhidrotic
ectodermal dysplasia with eruptive vellus hair cysts.
ectodermal dysplasia (Christ-Seimens-Touraine syndrome)-case report with a review.
Although the lesions are themselves anhidrotic
, the effect of hyperhidrosis of the surrounding skin, maceration and friction alter the appearance of the psoriasis, which retains its characteristic colour.
Sweating responses of normal, paraplegic and anhidrotic
ectodermal dysplasia: a clinical and pathologic study.
ectodermal dysplasia gene (EDA) undergoes alternative splicing and encodes ectodysplasin-A with deletion mutations in collagenous repeats.