an·tag·o·nist ( n-tg  -n st)n. 1. One who opposes and contends against another; an adversary. 2. The principal character in opposition to the protagonist or hero of a narrative or drama. 3. Physiology A muscle that counteracts the action of another muscle, the agonist. 4. Biochemistry A chemical substance that interferes with the physiological action of another, especially by combining with and blocking its nerve receptor. an·tag  o·nistic adj.an·tag o·nisti·cal·ly adv. |
ThesaurusLegend: Synonyms Related Words Antonyms
| Adv. | 1. |  antagonistically - in an antagonistic manner; "he behaves antagonistically toward his colleagues" |
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