In the absence of contraindications (such as QT lengthening or polymorphic ventricular tachycardia), amiodarone is generally the antiarrhythmic drug
of choice and has been validated in numerous clinical trials.
Blomstrom-Lundqvist inferred that the significantly better improvement in quality of life seen with ablation, compared with drug treatment, occurred because the ablated patients all came off antiarrhythmic drug
Patients received an implantable cardiac monitor for a two month run-in period, then were randomised to ablation with pulmonary vein isolation or antiarrhythmic drug
therapy with adequate dosages according to guidelines.
NASDAQ: CRME) (TSX: COM) has received a response from the US Food and Drug Administration regarding the regulatory path for Brinavess (vernakalant hydrochloride, IV), its antiarrhythmic drug
for the rapid conversion of recent onset atrial fibrillation, the company said.
Multiple clinical trials have established the superiority of CA over antiarrhythmic drug
therapy (AAD) for the maintenance of sinus rhythm and improvement of quality of life.
Quinidine, a Class la antiarrhythmic drug
with Ito and IKr blocker effects, has been shown to prevent induction of VF and suppress spontaneous ventricular arrhythmias in a clinical setting.
It's notable that antiarrhythmic drug
development has almost been stopped because the drugs don't work, with the possible exception of amiodarone, which requires an individualized risk/benefit assessment," according to Dr.
Various therapeutic options are available to treat patients with AF, and most patients will receive some form of antithrombotic therapy, a heart rate control agent, and potentially, an antiarrhythmic drug
for rhythm control.
Flecainide acetate is an antiarrhythmic drug
indicated for use in patients without structural heart disease for the prevention of paroxysmal supraventricular tachycardias, including atrioventricular reentrant tachycardia and other supraventricular tachycardias of unspecified mechanism associated with disabling symptoms as well as paroxysmal atrial fibrillation/flutter associated with disabling symptoms.
Amiodarone was temporarily stopped and it was substituted by Sotalol at a dose of 80mg BD (class II antiarrhythmic drug
with also class III actions) on consultation with Cardiologist.
options include amiodarone, dofetilide, dronedarone, flecainide, propafenone and sotalol.
The authors conducted a prospective study of the efficacy of sequential antiarrhythmic drug
therapy in SR maintenance after a successful ECV in individuals with chronic AF.