Subanalysis by Baseline Antiepileptic Drugs
(AEDs): Results from Perampanel Study 332 in Patients with Primary Generalized Tonic-Clonic Seizures (PGTCS)
Fycompa is a first-in-class antiepileptic drug
discovered and developed by Eisai.
Early child development and exposure to antiepileptic drugs
prenatally and through breastfeeding: a prospective cohort study on children of women with epilepsy.
1) Currently, no reliable, fast-acting, effective, long-term antiepileptic drugs
are licensed for use in avian medicine.
The FDA cited data from the Neurodevelopmental Effects of Antiepileptic Drugs
study, published in March 2013, which found that at age 6, children whose mothers had taken valproate products while pregnant had lower IQs, compared with those whose mothers took other antiepileptic drugs
Two randomized, double-blind, placebo-controlled studies are designed to evaluate the efficacy and safety of brivaracetam (5, 20 and 50 mg/day or 20, 50 and 100 mg/day) over 12 weeks in patients with partial onset epilepsy, not fully controlled despite treatment with one or two other antiepileptic drugs
This practice can provide economies in the prescription budget, but for patients and physicians it can lead to increased expenditures if the managed care organization requires the switching of patients controlled on a given formulation of antiepileptic drug
to another formulation.
Patients in the study who withdrew from antiepileptic drug
(AED) treatment were not significantly more likely to have seizure recurrence than were those who did not, thereby meeting the common secondary goal of discontinuing or reducing AEDs after epilepsy surgery Thus, the findings of this study may provide reassurance to neurologists who are hesitant to withdraw AEDs after surgery because of concerns that seizures may recur, Dr.
Three phase III trials of the drug have reported 28-day reductions in seizure frequency relative to placebo in patients who were taking one to three other antiepileptic drugs
I feel that valproate should not be a first choice antiepileptic drug
in women of childbearing potential," Dr.
Now, results of the new study suggest that antiepileptic drug
(AED) treatments may trigger schizophrenia-like behaviours in its users when given during the brain's developmental period.
Health issues that challenge women with epilepsy (WWE) and their healthcare providers include menstrual cycle influence on seizure activity, contraceptive-antiepileptic drug
interaction, pharmacokinetic change during pregnancy, teratogenicity of antiepileptic drugs
, breastfeeding, and the impact of antiepileptic drugs
on bone health and sexual function.