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folic acid
(redirected from antifolate)

   Also found in: Medical, Legal, Encyclopedia, Wikipedia 0.01 sec.
fo·lic acid  (flk, flk)
n.
A yellowish-orange compound, C19H19N7O6, of the vitamin B complex group, occurring in green plants, fresh fruit, liver, and yeast. Also called folacin, folate, vitamin Bc.

[Latin folium, leaf; see folium + -ic.]

folic acid [ˈfəʊlɪk ˈfɒl-]
n
(Chemistry / Elements & Compounds) any of a group of vitamins of the B complex, including pteroylglutamic acid and its derivatives: used in the treatment of megaloblastic anaemia Also called folacin
[from Latin folium leaf; so called because it may be obtained from green leaves]

folic acid  (flk, flk)
A water-soluble vitamin belonging to the vitamin B complex that is necessary for the formation of red blood cells and important in embryonic development. It is also the parent compound of coenzymes in various metabolic reactions. Folic acid is found especially in green leafy vegetables, liver, and fresh fruit. Deficiency of folic acid in the diet results in anemia. Chemical formula: C19H19N7O6.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.folic acid - a B vitamin that is essential for cell growth and reproduction
B complex, B vitamin, B-complex vitamin, vitamin B, vitamin B complex, B - originally thought to be a single vitamin but now separated into several B vitamins
Translations
folic acid [ˌfəʊlɪkˈæsɪd] Nácido m fólico
folic acid
nFolsäure f


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Far from giving up, he thought if folic acid was aggravating the production of white blood cells, a chemical -- perhaps an antifolate -- could block the growth of white blood cells to leukemia.
Recently two antifolate-based combinations with apparently higher efficacy than older regimens have emerged the pemetrexed/cisplatin regimen and the raltitrexed/oxaliplatin regimen Another interesting study is called, "The emerging role of antifolates in the treatment of malignant pleural Mesothelioma" by Karim Fizazi, William J.
It is, in part, why we believe there exists a significant need for both a safer and more effective antifolate treatment alternative.
 
 
 
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