antigenic determinant


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Related to antigenic determinant: hapten, Clonal selection

antigenic determinant

n
(Biochemistry) the specific part of an antigen molecule to which an antibody becomes attached

ep•i•tope

(ˈɛp ɪˌtoʊp)

n.
a site on an antigen at which an antibody can bind, the molecular arrangement of the site determining the specific combining antibody. Also called antigenic determinant .
[1970–75; epi- + -tope < Greek tópos place; compare topo-]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.antigenic determinant - the site on the surface of an antigen molecule to which an antibody attaches itself
immunology - the branch of medical science that studies the body's immune system
site, situation - physical position in relation to the surroundings; "the sites are determined by highly specific sequences of nucleotides"
antigen - any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)
References in periodicals archive ?
Mapping of antigenic determinant regions of the Bor56 protein of Orientia tsutsugamushi.
One such method comprises a) contacting said bodily fluid with said MuSK or an antigenic determinant thereof; and b) detecting any antibody-antigen complexes formed between said receptor tyrosine kinase or an antigenic fragment thereof and antibodies present in said bodily fluid, wherein the presence of said complexes is indicative of said mammal suffering from said neurotransmission or developmental disorders.
A better understanding of the structure of the allergen and its gene would allow design of non-allergenic fragments carrying the antigenic determinant similar to the hypoallergen.
coli strain F18 (F18ab and F18ac), which possess the variant-specific antigenic determinant "b" and "c", respectively, in addition to a common antigenic determinant "a".
The antigenic determinant sites located on the N protein were determined according to the specific binding of a mAb to the particular yeast-displayed protein.
Identification of an antigenic determinant on the $2 domain of the severe acute respiratory syndrome coronavirus spike glycoprotein capable of inducing neutralizing antibodies.
Our phylogenetic data were based on analysis of the HMPV F protein, one of two viral glycoproteins considered the major antigenic determinant in RSV (11).
The antigenic determinant of this antibody is unique, enabling it to be paired with any other PSA antibody.