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antimetabolite |
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antimetabolite [ˌæntɪmɪˈtæbəˌlaɪt] n
(Medicine / Pharmacology) any drug that acts by disrupting the normal growth of a cell. Sulfonamide drugs are antimetabolites and some antimetabolites are used in cancer treatment ThesaurusLegend: Synonyms Related Words Antonyms
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| Certain conventional chemotherapies, such as the antimetabolite gemcitabine, exert their anticancer activity at the S-phase of the cell cycle. Surgeons began to find success with purine antimetabolites and with antilymphocytic globulin, developed by an upstart ex-football player named John Najarian. He starts with Paul Ehrlich's antitreponemal arsenicals and ends with the antisense agents now in early clinical trials for the treatment of autoimmune diseases and cancer, covering in the process the development of antibacterial and antiviral agents, vaccines, antimetabolites, and hormone-based antineoplastic agents. |
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