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antimitotic |
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| These studies also revealed that serum binding proteins can be protective of DNA antimitotic activity, but because fetuses and newborns have lower concentrations of serum proteins than adults, they could be more vulnerable. The caspase inducer encompassed by the SBIR grant is one of a new class of antimitotic agents. First, to what extent does the antimitotic effect of chlorpyrifos extend to its major metabolites, chlorpyrifos oxon, the active inhibitor of cholinesterase, or trichloropyridinol, the catabolic product that is prominent in fetal brain after maternal chlorpyrifos exposure (24), which has been identified almost ubiquitously in urine samples of U. |
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