antimutagen


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Related to antimutagen: antitoxic

antimutagen

(ˌæntɪˈmjuːtədʒən)
n
(Genetics) any substance that acts against a mutagen
References in periodicals archive ?
Chlorophyllin: a potent antimutagen against environmental and dietary complex mixtures.
Interest in Ellagic acid has increase greatly during the last decade due to its effectiveness as an antimutagen and anticarcinogen and its potential as an inhibitor of chemically-induced cancer.
White tea was a much more powerful antimutagen than green tea," reports Oregon's Gilberto Santana-Rios, a coauthor of the study.
Among these, the [TABULAR DATA FOR TABLE III OMITTED] major component vitamin C, due to its antioxidant and chelating effects, has been already observed to act as anticarcinogen, antimutagen, and anticlastogen, respectively, in different test systems (Mirvish, 1975; Parshad et al.
Resveratrol was found to act as an antioxidant and antimutagen and to induce phase II drug-metabolizing enzymes (anti-initiation activity); it mediated anti-inflammatory effects and inhibited cyclooxygenase and hydroperoxidase functions (antipromotion activity); and it induced human promyelocytic leukemia cell differentiation (antiprogression activity).
Galangin was the most active antimutagen among the flavonoids tested such as chrysin, tectochrysin, chrysin-5-methylether, galangin, galangin-S-methylether, pinocembrin, pinobanksin, apigenin and isalpinin.
Chlorophyllin (CHL) is a potent antimutagen in vitro, an effective anti-carcinogen in several animal models, and significantly reduced urinary biomarkers of aflatoxin B(1) (AFB(1)) exposure in a human population.
Most of the polymeric tannins exerting an antimutagen activity on 2-Aminoanthracene and other nitroaromatic indirect-acting mutagens, can be classified as blocking agents since they inhibit the conversion of the latter to ultimate carcinogens.
Key words: Antimutagen, Anticarcinogen, Phyllanthus amarus, Plant, Alkaline elution, Mutation assay
Recently, natural plants have received much attention as sources of biologically active substances including antioxidants, antimicrobials, antimutagens and anticarcinogens nutraceuticals.