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antimycin

   Also found in: Medical, Wikipedia 0.02 sec.
an`ti`my´cin    (ăn`tĭ`mī´sĭn)
n.1.one of several antibiotic substances produced by several species of Streptomyces, active against various fungi. They are used only experimentally, not in medicine. The two best-known antimycins are antimycin A1 (C28H40N2O9) and antimycin A3 (C26H36N2O9). They are notable for their mechanism of action, interference with the proton pumping mechanism of fungi.
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Noun1.antimycin - a crystalline antibiotic active against various fungi
antibiotic, antibiotic drug - a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections; "when antibiotics were first discovered they were called wonder drugs"


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5 [micro]M antimycin A, 20 mM 2deoxyglucose and 10 [micro]M A23187, respectively) for 4 hours.
] formation was substantially (by 30%) enhanced upon illumination of these cells in the presence of 10 [micro]M antimycin A (ANM), an inhibitor of the Complex III at the site of ubiquinol-cytochrome c reductase in the respiratory chain of mitochondria [39].
Researchers affiliated with the National Cancer Institute and other groups have extracted compounds from marine sponges and corals that inhibit the growth of tumor cells, and a group from the Scripps Institution of Oceanography has isolated marine bacteria closely related to the terrestrial organisms from which antimycin antibiotics were originally derived.
 
 
 
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