pustulata (rubiadin and soranjidiol) and its methylated derivates (rubiadin 1-methyl ether and soranjidiol 1-methyl ether) such as antitumoral
agents against human breast cancer cell line.
A second in vivo study tested the antitumoral
activity of U.
The antitumor activity in vivo of three preparations from the total flavonoid fraction revealed that the total flavonoid fraction presented high antitumor activity, and showed a high potential for its development as antitumoral
1996), while the C-28 aldehyde derivative of betulonic acid has been shown to have a higher antitumoral
activity than that of the parent metabolite (Kim et al.
Previous studies showed that "constituents of C violaceum" possessed antibiotic and antichagasic (Duran and Menck 2001), antitumoral
(Melo et al.
In addition to its antidiabetic activity, an in vitro antitumoral
activity was described and related to an unusual nitrogenated compound isolated from the leaves (Lim et al.
Duguetine and duguetine [beta]-N-oxide caused considerable antitumoral
activity in every cell lines evaluated, although duguetine was more active against trypomastigote forms ([IC.
Volatile oils from a broad spectrum of plant species have shown antinociceptive, antiinflammatory, antimicrobial, antiviral, antitumoral
and antioxidant activities (Asekun et al.
In the light of these results, it is not very likely that constituents 1-5 are responsible for the antitumoral
activity of the Old enlandia herbs.
properties of triterpene acids like betulinic acid and oleanolic acid have been shown.
The aim of this study was therefore to demonstrate, using an MTS colorimetric method to evaluate cell viability, the antitumoral
action of mitraphylline as compared to two well-known citostatic agents, ciclophosphamide and vincristine.
Onxeo stated that this new patent significantly strengthens the company's intellectual property portfolio by protecting several conjugated nucleic acid molecules including AsiDNA, as well as the pharmaceutical compositions and their therapeutic uses, especially for treating cancer, standalone and in combination with a DNA -damaging antitumoral
agent (such as radiotherapy, chemotherapy or other tumour DNA damage-inducing agents).