apolipoprotein


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Related to apolipoprotein: Apolipoprotein B, Apolipoprotein A1, Apolipoprotein C2

ap·o·lip·o·pro·tein

 (ăp′ə-lĭp′ō-prō′tēn′, -tē-ĭn, -lī′pō-)
n.
Any of various proteins that bind to insoluble lipids to form the soluble lipoproteins, such as HDL and LDL, that transport triglycerides and cholesterol within the body.

apolipoprotein

(ˌæpəˌlɪpəʊˈprəʊtiːn; -ˌlaɪ-)
n
(Biochemistry) any of a group of glycoproteins that form part of the structure of lipoproteins, some of which have been associated with Alzheimer's disease
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Table 31: World Historic Review for Apolipoprotein B Tests by
Editor's Note: Those who used fish oil over follow-up had better scores of cognitive function at any time over the course of the study; however, the effect mainly occurred among those who were not carriers of the apolipoprotein E4 gene, which has been linked with Alzheimer's disease.
Association of apolipoprotein B and nuclear magnetic resonance spectroscopy-derived LDL particle number with outcomes in 25 clinical studies: assessment by the AACC Lipoprotein and Vascular Diseases Division Working Group on Best Practices.
The apolipoprotein A-1 and apolipoprotein B effects mirrored the effects of HDL and LDL.
Studies have previously found an inverse relationship between high density lipoprotein cholesterol (HDL-C) or apolipoprotein A-1 levels and cardiovascular disease.
Several studies have shown that [epsilon]2 allele is associated with low levels of TC, LDL-C and apolipoprotein B (apo B), whereas for [epsilon]4 allele the opposite is observed (7).
Masoud Toloue, Senior Scientist at Bioo Scientific, "Elevated plasma concentration of Apolipoprotein B (ApoB) is an established risk factor for atherosclerosis and a better indicator of heart disease than total cholesterol or LDL alone making it a highly sought after pharmaceutical lipid target.
Apolipoprotein E (apoE) genotyping was performed by serial invasive signal amplification reaction using genomic DNA.
But for all other lipid parameters--LDL, non-HDL cholesterol, apolipoprotein B, and triglycerides--there were no significant differences among the three contraceptive formulations.
At baseline, the subjects' mean age was 69 years; 26% were known to be positive for the apolipoprotein E4 allele (ApoE4).
Albert Einstein College of Medicine of Yeshiva University (Bronx, NY) has patented methods of using of the sizes and levels of high-density lipoprotein (HDL) and low-density lipoprotein (LDL) particles, the -641 allele of the promoter of the gene encoding apolipoprotein C-3 (APOC-3), the 405 allele of the gene encoding cholesteryl ester transfer protein (CETP), and plasma levels of insulin-like growth factor-1 (IGF-1), adiponectin, CETP and APOC-3, for determining and increasing an individual's likelihood of longevity and of retaining cognitive function during aging, and for determining and decreasing an individual's likelihood of developing a cardiovascular-, metabolic- or age-related disease.