Seventy-five percent of the potential cost saving lay in the last item, administering aprotinin
based upon clinical standards.
During the course of trial, evidence was presented that the administration of drugs Amicar or Aprotinin
before surgery diminishes the risk of excessive bleeding, whereas ingestion of aspirin enhances such risk.
An experimental study of the effect of aprotinin
on intestinal adhesion formation.
BNP Detection: Blood samples were collected with chilled tubes containing ethylenediaminetetraacetic acid and aprotinin
1 d before and 3 d after the operation through the peripheral vein.
4]; 1 mM NaF; 1 mM PMSF; and 10 [micro]g/mL each of aprotinin
and leupeptin) and stored at -20[degrees]C.
The effect of aprotinin
, tranexamic acid, and aminocaproic acid on blood loss and use of blood products in major pediatric surgery: a meta-analysis.
The second sample was collected in a tube containing, in addition to EDTA-2K, aprotinin
, as a protease inhibitor (50 |xl of aprotinin
solution/ml whole blood).
Studies on the mechanisms of action of aprotinin
and tranexamic acid as plasmin inhibitors and antifibrinolytic agents.
This was then followed by two washes in PBS with aprotinin
This has perhaps been best voiced in a study published in the New England Journal of Medicine several years ago about the use of aprotinin
in cardiac surgery.
Following application to the tooth extraction site, thrombin converts fibrinogen to an unstable fibrin clot and aprotinin
prevents clot degradation (2), (3).