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asparaginase

   Also found in: Medical, Encyclopedia, Wikipedia 0.04 sec.
as·par·a·gin·ase  (-spr-j-ns, -nz)
n.
An enzyme isolated from bacteria that catalyzes the hydrolysis of asparagine and is used in the chemotherapeutic treatment of leukemia.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.asparaginase - antineoplastic drug (trade name Elspar) sometimes used to treat lymphoblastic leukemia
Elspar
antineoplastic, antineoplastic drug, cancer drug - any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function


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Treatment protocols include the use of asparaginase, corticosteroids (prednisone and dexamethasone), an anthracycline (doxorubicin), mercaptopurine, methotrexate, and vincristine.
Proficiency of balance in children and youth who have had acute ... by Barr, Ronald D. / Physical Therapy
Food and Drug Administration in February 1994 and is now indicated as a component of a multi-agent chemotherapeutic regimen for patients with acute lymphoblastic leukemia as up-front treatment in first-line therapy and for patients who have had hypersensitivity to asparaginase.
Enzon Pharmaceuticals Secures Supply of Oncaspar by Business Wire
During May, the FDA further limited the distribution of ONCASPAR to patients who are hypersensitive to other forms of L- asparaginase.
Enzon Reports Fourth Quarter and Fiscal Year Results for 1999 by Business Wire
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