A 20-year-old woman, with no history of medical problems, was admitted to the hospital on February 4, 2002, with a 3-week history of asthenia
, myalgia, low-grade fever, urinary retention, and blurred vision.
In these patients, the most frequent clinical adverse experiences are dizziness, dyspnea, chest pain, asthenia
, cough, diarrhea, and hypotension.
Other common adverse reactions included anemia, asthenia
, diarrhea, ocular/visual disturbances, fluid retention, alopecia, hepatic dysfunction, mucositis, and renal dysfunction.
Moderate to severe adverse events occurring in more than 5 percent of patients receiving Viread included rash (rash, pruritis, maculopapular rash, urticaria, vesiculobullous rash and pustular rash), headache, pain, diarrhea, depression, back pain, fever, nausea, abdominal pain, asthenia
and anxiety (Study 903).
The most common adverse effects causing patients to discontinue medication in clinical trials include, fatigue (4 percent), bradycardia (slow heartbeat -- 3 percent), dyspnea (labored breathing -- 3 percent), proarrhythmia (potential for a drug to induce an arrhythmia -- 3 percent), asthenia
(weakness -- 2 percent) and dizziness (2 per.
The most common adverse events in this study possibly related to Dacogen were myelosuppression, fatigue, nausea, asthenia
, dyspnea, diarrhea, and pneumonia.
At lesser frequencies by chills, nausea, vomiting, headache, urinary frequency, rhinitis, dizziness, vasodilation, lacrimation, asthenia
, diarrhea and dyspepsia have been documented.
The most common (]greater than or equal to] 10%) adverse events observed in clinical trials of FENTORA were nausea, vomiting, application site abnormalities, fatigue, anemia, dizziness, constipation, edema, asthenia
, dehydration, and headache.
Adverse events related to CINTREDEKIN BESUDOTOX or catheter placement were consistent with adverse events observed in Phase 1 studies of CINTREDEKIN BESUDOTOX administered as monotherapy in patients with recurrent malignant glioma and, regardless of causality, included asthenia
, headache, alopecia, and nausea.