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An antibody that reacts with the cells, tissues, or native proteins of the individual in which it is produced.


n, pl -bodies
(Biochemistry) an antibody reacting with an antigen that is a part of the organism in which the antibody is formed


(ˌɔ toʊˈæn tɪˌbɒd i, -ˈæn ti-)

n., pl. -bod•ies.
an antibody that an organism produces against any of its own components.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.autoantibody - an antibody acting against tissues of the organism that produces it
rheumatoid factor - autoantibody that is usually present in the serum of people with rheumatoid arthritis
antibody - any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
References in periodicals archive ?
While multiple mechanisms are likely involved in CFS and MCS, the female predominance, increased frequency of Hashimoto's thyroiditis (HT)-related autoantibodies and/or anti-nuclear antibodies (ANA), and total IgE results, which are not highly elevated, suggest classic allergies are less likely and autoimmune mechanisms are more likely to play at least a partial role in the hypersensitivity reactions in a subgroup of patients.
Autoantibodies linked to celiac disease were found in 808 youngsters.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with characteristic organ involvement and autoantibodies production.
GSK said the approval marks the first subcutaneous self-injection treatment option for patients with SLE, which is the most common form of lupus, a chronic, incurable autoimmune disease producing autoantibodies that can attack almost any system in the body.
Systemic Lupus Erythematosus (SLE) is reportedly the most common form of lupus, a chronic, incurable autoimmune disease producing autoantibodies that can attack almost any system in the body.
genavense infection resulting from the presence of neutralizing anti-interferon-[gamma] (anti-IFN-[gamma]) autoantibodies was diagnosed.
The KRONUS 3-Screen Islet Cell Autoantibody ELISA Assay Kit is for the simultaneous and nondifferential detection of GAD and/ or IA-2 and/or ZnT8 autoantibodies in human serum.
In subsequent decades, the presence of various autoantibodies such as glutamic acid decarboxylase antibody, microinsulin antibody, and zinc transporter antibody were reported.
reported neurological autoantibodies (NAAs) among patients with epilepsy of unknown etiology.
While individual autoantibodies seen in systemic sclerosis (SSc) are known to be associated with greater or lesser risk of cardiopulmonary involvement, in this study nailfold vascularization patterns independently predicted pulmonary artery hypertension or interstitial lung disease.
Twenty years ago in Clinical Chemistry, cardiac troponin I (cTnI) (3) autoantibodies to the stable portion of cTnI near the carboxyterminal end of the molecule were first identified as an etiology for false-negative cTnI results (1).
sup][9] Among SmD1 peptides, the SmD1-amino-acid 83-119 peptide (SmD1[sub]83-119), which was discovered through epitope mapping using 13-mer peptides overlapping by ten amino acids and sera from adult SLE patients, was described as a major epitope targeted by autoantibodies in adult SLE sera.