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 (ôk′sə-trŏf′ĭk, -trō′fĭk)
Requiring one or more specific substances for growth and metabolism that the parental organism was able to synthesize on its own. Used with respect to organisms, such as strains of bacteria, algae, or fungi, that can no longer synthesize certain growth factors because of mutational changes.

[Greek auxein, to increase; see auxin + -trophic.]

aux·ot′ro·phy (ôk-sŏt′rə-fē) n.
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References in periodicals archive ?
Therefore, the auxotrophic mutants which are unable to multiply in the environment were designed.
Of the 12 isolates, 7 were double auxotrophic mutants with G6P and G3P (mean MIC 384 mg/L), 3 were auxotrophic only for G3P (mean MIC 597 mg/L), and 2 were capable of using both substrates and exhibited high-level resistance (MIC >1,024 mg/L).
1977) The isolation and preliminary characterisation of auxotrophic and analogue resistant mutants of the moss, Physcomitrella patens.
The colonies which showed growth on complete medium (containing all the essential amino acids) but not on minimal medium were considered as auxotrophic (mutants).
Mutants of Psm using pTn5cat1 were obtained through conjugal transfer of pMC505 containing the transposable element from the auxotrophic strain E.
Parascandola, "Performance of the auxotrophic Saccharomyces cerevisiae BY4741 as host for the production of IL-1[beta] in aerated fed-batch reactor: role of ACA supplementation, strain viability, and maintenance energy," Microbial Cell Factories, vol.
L- lysine Production by the Homoserine Auxotrophic Mutant of Corynebacterium glutamicumin Stirrer Fermenter.
Inhibition of prolidase activity by nickel causes decreased growth of proline auxotrophic CHO cells.
This new auxotrophic selection system is a significant upgrade to the existing XS Microbial Expression Technologies and is applicable to all Lonza E.
Considering the fact, the present study was intended to select suitable maintenance medium for the auxotrophic mutant Micrococcus glutamicus [AB.
0] strains allowed to identify some differential phenotypes, for example, amino acid requirements are not exactly the same for these genetically defined strains and the auxotrophic phenotype of the [(p)ppGpp.