Also found in: Medical, Encyclopedia.


The cytoplasm of an axon.

[Greek axōn + -plasm.]

ax′o·plas′mic (-plăz′mĭk) adj.


of or relating to the axoplasm
References in periodicals archive ?
In Section 4, the united model of signal propagation is described including the interacting electrical signal (action potential), the mechanical wave in the surrounding biomembrane, and the wave in the axoplasmic fluid inside the nerve fibre.
Mercury damages the nerves in several ways: it interferes with membrane and receptor functions, and neurotransmitter transport and metabolism; it interrupts cytoskeletal proteins, and interferes with axoplasmic flow and signal transduction; it interferes with cell respiration, energy metabolism and others.
Studies have demonstrated that mechanical stress could cause physical alterations in the ONH, such as misalignment of the fenestrate in lamina cribrosa, which may lead to axoplasmic flow obstruction due to its back bowing.
2 Since the optic nerve sheath can be traced as continuation of the subarachnoid space, transmission of effects of raised ICP to the optic nerve causes disruption of the axoplasmic flow, swelling of axons, leakage of water and proteins with resultant optic disc swelling, or papilledema.
It is thought that obstruction of axoplasmic flow causes axons to swell acutely, giving rise to microvesicular changes.
Although the mechanism of drusen formation has not been fully determined, it is believed that congenitally small disc and scleral channels may cause axoplasmic flow stasis and ganglion cell axon death.
It is a microtubule depolymerizing agent and causes blocking of the axoplasmic flow in colchicine induced rat model of Alzheimer Disease (cAD) [1, 2].
Increased intraocular pressure (IOP) is a consequence of abnormal high resistance to aqueous humor drainage via the trabecular meshwork, causing anterograde/retrograde axoplasmic flow impairment (the mechanical theory of glaucoma), and it is the leading risk factor for RGCs apoptosis in glaucoma [63].
In order to provide a scaffold for smooth and unbranched axoplasmic migration into the Schwann cell tube of the distal stump, the continuity of the severed N.
These peptides are synthesized in the x-organ (XO) and travel via axoplasmic flow to the synaptic terminals of the sinus gland (SG) where they are secreted into the hemolymph (see Hopkins, 2012, for review).
They represent retinal hyaline corpuscles resulting from impaired axoplasmic transport of retinal ganglion cells of optic nerve in front of the lamina cribrosa [1, 2].