azathioprine


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Related to azathioprine: prednisone, methotrexate

az·a·thi·o·prine

 (ăz′ə-thī′ə-prēn′)
n.
An immunosuppressive agent used to prevent organ rejection in kidney transplant recipients and to treat severe rheumatoid arthritis.

[Probably from az(o)- + thio- + p(u)rine.]

azathioprine

(ˌæzəˈθaɪəˌpriːn)
n
(Pharmacology) a synthetic drug that suppresses the normal immune responses of the body and is administered orally during and after organ transplantation and also in certain types of autoimmune disease. Formula: C9H7N7O2S
[C20: from aza- + thio- + p(u)rine]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.azathioprine - an immunosuppressive drug (trade name Imuran) used to prevent rejection of a transplanted organazathioprine - an immunosuppressive drug (trade name Imuran) used to prevent rejection of a transplanted organ
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease
Translations

azathioprine

n azatioprina
References in periodicals archive ?
Immunosuppressant therapy comprised cyclosporine, azathioprine and prednisolone.
Because of UC activation 1 month previously, azathioprine and prednisolone were initiated at initial doses of 50 and 40 mg/day, respectively.
Immunosuppressive treatment with azathioprine may be associated with an increased risk of squamous cell carcinoma in organ transplant recipients, but does not appear to increase the risk of basal cell carcinoma or keratinocyte cancers overall, according to a systematic review and meta-analysis of 27 studies.
For the last thirty years, corticosteroids, either alone or in combination with azathioprine, have been the foundations of drug therapy for patients with AIH.
The drugs commonly used are corticosteroids, sulfasalazine and immunesuppressive drugs such as azathioprine (AZA).
In cases when corticosteroid therapy does not give desired results or the therapy has been discontinued due to the development of side-effects, there are other pharmacological options, such as methotrexate, mycophenolate mofetil, cyclophosphamide, chloroquine, azathioprine, thalidomide and infliximab.
The itching can be very intense and the sufferer might end up scratching their skin for hours and hours but the best thing for him was to undergo a systemic treatment, which involved him taking azathioprine to reduce the inflammation.
Simultaneous determination of 6-thioguanine and methyl 6mercaptopurine nucleotides of azathioprine in red blood cells by HPLC.
Objective To document the efficacy and safety of azathioprine pulse therapy in the treatment of psoria
Janssen Biotech, a biotechnology company that was founded in Philadelphia, has received FDA approval for Simponi (golimumab) to treat moderately to severely active ulcerative colitis in adult patients with corticosteroid dependence or an inadequate response to or failure to tolerate oral aminosalicylates, oral corticosteroids, azathioprine, or 6-mercaptopurine, it was reported yesterday.
Azathioprine is immune suppressive drugs to treat diseases such as leukemia; acute lymphoblastic, inflammatory bowel disease and rheumatoid arthritis are used.