azathioprine


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Related to azathioprine: prednisone, methotrexate

az·a·thi·o·prine

 (ăz′ə-thī′ə-prēn′)
n.
An immunosuppressive agent used to prevent organ rejection in kidney transplant recipients and to treat severe rheumatoid arthritis.

[Probably from az(o)- + thio- + p(u)rine.]

azathioprine

(ˌæzəˈθaɪəˌpriːn)
n
(Pharmacology) a synthetic drug that suppresses the normal immune responses of the body and is administered orally during and after organ transplantation and also in certain types of autoimmune disease. Formula: C9H7N7O2S
[C20: from aza- + thio- + p(u)rine]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.azathioprine - an immunosuppressive drug (trade name Imuran) used to prevent rejection of a transplanted organazathioprine - an immunosuppressive drug (trade name Imuran) used to prevent rejection of a transplanted organ
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease
Translations

azathioprine

n azatioprina
References in periodicals archive ?
Cyclosporin, methotrexate, oral corticosteroids, azathioprine,
Effect of allopurinol on clinical outcomes in inflammatory bowel disease nonresponders to azathioprine or 6-mercaptopurine.
Control group: no treatment control group (diabetic) daily cc 140 solution of fructose (10%) received group 1 to 4 (treatment of diabetes) after receiving the oral solution of fructose (10%) for 98 days, respectively, kg/bw mg/(3/5, 5/7, 15 and 21) received intra-peritoneal injection drug azathioprine.
Azathioprine is still widely used for moderate to severe lupus in 2012.
The study, known as PANTHER-IPF (Prednisone, Azathioprine, and N-acetylcysteine; A Study That Evaluates Response in Idiopathic Pulmonary Fibrosis), was designed to evaluate the effectiveness of a triple-therapy regimen in slowing disease progression and improving lung function in patients with moderate to severe IPF.
Many clinicians also choose not to prescribe azathioprine during early pregnancy or in the third trimester.
In the trial, known as the Aspreva Lupus Maintenance Study (ALMS), 227 patients with lupus kidney disease who had been successfully induced into remission with either Cytoxan[R] (cyclophosphamide) or CellCept[R] received either CellCept[R] or azathioprine to maintain that remission.
Azathioprine (AZA) is not approved by the United States Food and Drug Administration (FDA) for the treatment of Crohn's disease; however, it is widely used by gastroenterologists and other physicians in the U.
The patients were then randomized to treatment: 169 infliximab monotherapy, 170 azathioprine monotherapy, or 169 infliximab plus azathioprine combination therapy.
Thiopurine methyltransferase (TPMT) is a cytosolic enzyme that catalyzes the S-methylation of aromatic and heterocyclic sulfhydryl compounds, including mercaptopurine (MP), thioguanine (TG), and azathioprine (AZA) (1).
His current medications included prednisone, azathioprine, furosemide, digoxin, warfarin, ateuolol, atorvastatin, and co-trimoxazole.