azidothymidine


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Related to azidothymidine: nevirapine

a·zi·do·thy·mi·dine

 (ə-zī′dō-thī′mĭ-dēn′, ə-zē′-, ăz′ĭ-)
n.
See AZT.

azidothymidine

(əˌzaɪdəʊˈθaɪmɪˌdiːn)
n
an antiretroviral drug used to treat HIV/AIDS

AZT


Trademark.
azidothymidine: an antiviral drug used in the treatment of AIDS. Compare zidovudine.
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References in periodicals archive ?
Macrocytic anaemia was, however, more common among HIV-infected patients, most likely due to the use of azidothymidine.
The management of HIV/AIDS, which involves medications such as Azidothymidine (AZT), has been reported to have adverse effect on the auditory function of individuals infected with HIV/AIDS.
Shortly after the identification of the virus, scientists began working on possible treatments, culminating in the first anti-viral treatment for HIV, called azidothymidine (AZT).
The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex.
HAART regimens included two nucleoside reverse transcriptase inhibitors (NRTIs), either azidothymidine plus didanosine or stavudine plus lamivudine, and one nonnucleoside reverse transcriptase inhibitor (NNRTI), nevirapine.
In this study, it was aimed to investigate the effects of a new synthetic compound, platinum azidothymidine, on inhibition of telomerase and Bcl-2 expression in hepatocellular carcinoma compared to azidothymidine.
In 1986, under pressure from AIDS groups, the agency made the unapproved investigational drug azidothymidine (AZT) available on a "compassionate use" basis to patients outside of formal clinical trials.
The late 1980s through the mid-1990s introduced antiretroviral medications such as azidothymidine, dideoxyinosine, dideoxycytidine, protease inhibitors, combination drug therapy and Highly Active Antiretroviral Therapy (HAART).
By contrast, BNO-1055 significantly attenuated the uptake of the purine analog fludarabine and the pyrimidine analogs azidothymidine and gemcitabine.
By 1986, azidothymidine (AZT), an antiretroviral that interferes with the replication of the HIV virus, was widely prescribed because of its apparent ability to extend the life of some infected people (Strug et al.
This retrospective study of healthcare workers who had occupational exposure to HIV showed an 81% reduction in seroconversion in those who took azidothymidine (azidothymidine/zidovudine) for 28 days following exposure [3].