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basement membrane

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
basement membrane
n.
A thin, delicate layer of connective tissue underlying the epithelium of many organs. Also called basement lamina.


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If the basement membrane misbehaves, then the cell misbehaves," comments Raghu Kalluri, a matrix biology specialist at Harvard Medical School in Boston.
The illustrated chapters include fixation and processing, microtomy, frozen sections, hematoxylin and eosin, Gram stain, myobacteria, Heliobacter pylori, spirochetes, fungi, trichrome stains, reticulin, elastin stains, basement membranes, mucin stains, amyloid, and immunohistochemistry.
They look remarkably like a structure seen in cancer cells called invadopodia that are believed to have the same function, but modeling this part of metastasis in the lab has proven impossible so far because nobody has figured out how to make a basement membrane in a dish.
 
 
 
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