Congratulations to John Chapman for submitting batrachotoxin
from the poison dart frog, Phyllobates terribili, as the poison used in the October 2009 "Lily Robinson and an Assassin's Tracks.
A] receptor ligand sites, the batrachotoxin
site of the sodium channel (site 2) (Catterall et al.
Simply put, the patches I left for him were embedded with a highly lethal concentration of batrachotoxin from the poison-dart frog Phyllobates terribilis.
These dendrobatid frogs are the origin of the batrachotoxins (BTXs)--batrachotoxin, homobatrachotoxin, and batrachotoxin-A.
Daly and Myers found that they could use the presence of one alkaloid, batrachotoxin, to show that several species had a common ancestor.
Some alkaloids, such as batrachotoxin, have helped neurobiologists study sodium channels -- molecular pores in nerve cell membranes that help control the excitation of nerve cells.
Birds in the genera Pitohui and Ifrita carry batrachotoxins, the same compounds found in some of the poison frogs of the Americas.
These beetles, each only about 7 millimeters long, live in the same regions as the birds do and carry batrachotoxins, Dumbacher and his colleagues report in the Nov.
Members of Central and South American rainforest tribes hunt with darts dipped in batrachotoxins
from dart-poison frog skin.
At the time, the alkaloids, called batrachotoxins
, had been found in only one other source in nature, the Phyllobates poison dart frogs on the other side of the world--in Colombia and Panama.