beta-lactam antibiotic


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beta-lactam antibiotic

n.
Any of a class of broad-spectrum antibiotics, such as the penicillins and the cephalosporins, that contain a beta-lactam ring.
References in periodicals archive ?
The MaxSignal Beta-Lactam ELISA Test Kit was developed to ease these concerns and assure that food is free of beta-lactam antibiotic residues.
The best evidence right now is that for simple cellulitis (no purulence, abscess, or exudate), treatment with a beta-lactam antibiotic is the best option.
On December 30, 2003, Advancis was issued United States Patent 6,669,948 entitled "Antibiotic Product, Use and Formulation Thereof" regarding the pulsatile delivery of beta-lactam antibiotic products, a class of broad spectrum antibiotics.
They also documented that the new beta-lactam antibiotic ceftaroline, recently approved by the Food and Drug Administration, is able to bind to the allosteric domain and trigger the same allosteric opening of the active site.
The acquisition includes Orchid's beta-lactam antibiotic formulations manufacturing complex (comprising cephalosporin, penicillin and carbapenem facilities) and pharmaceutical research and development (R&D) facility at Irungattukottai, Chennai, as well as its generic injectable dosage-form product portfolio and pipeline.
The combination of OP0595 with a beta-lactam antibiotic targets severe infections caused by Enterobacteriaceae, including multi-drug-resistant strains.
Methicillin, a penicillinase-stable beta-lactam antibiotic, was introduced in 1961 to battle the problem of increasing penicillin resistance in Staphylococcus aureus.
NYSE MKT: SYN), a clinical-stage company focused on developing therapeutics to protect the microbiome while targeting pathogen-specific diseases, presented data from its novel SYN-004 program that demonstrated SYN-004 protected the gut microbiome from damage often caused by the intravenous (IV) beta-lactam antibiotic, ceftriaxone, in a pilot study of humanized pigs.
para]]-- Successful Clinical Development Would Enable Company's Microbiome-Protecting Therapeutics to Cover all Three Beta-Lactam Antibiotic Classes --[[/para]]
As was observed decades later with MRSA, previous treatment with a beta-lactam antibiotic, in this case penicillin, increased the chances of isolating a penicillin-resistant strain.
In a rabbit model, biofilms on Foley catheter surfaces were highly resistant to high levels of amdinocillin, a beta-lactam antibiotic (30).
MethylGene has designed and developed small molecules that inhibit the beta-lactamase enzymes, which are a major cause of resistance to these widely utilized antibiotics and these small molecules may be combined with any beta-lactam antibiotic.

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