bile acid


Also found in: Thesaurus, Medical, Legal, Acronyms, Encyclopedia, Wikipedia.
Related to bile acid: bile salt

bile acid

n.
Any of the liver-generated steroid acids, such as cholic acid, that commonly occur in the bile in combination with glycine and taurine as sodium salts.

bile′ ac`id


n.
any of various steroid acids that emulsify fats during digestion. Compare bile salt.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.bile acid - any of the steroid acids generated in the liver and stored with bile
steroid - any of several fat-soluble organic compounds having as a basis 17 carbon atoms in four rings; many have important physiological effects
cholic acid - an insoluble crystalline acid present in bile
Translations
Gallensäure
acido biliare
References in periodicals archive ?
Chief Medical Officer of NGM Bio commented, "We are excited to see the robust biology of NGM282 translate into this significant beneficial effect on key biomarkers of hepatobiliary injury in patients afflicted with PBC, a disease exacerbated by disordered bile acid synthesis.
The researchers then analyzed the samples for their bile acid binding, swelling and gelling properties.
Effects of dietary TCDF on gene expression profiles: genes associated with bile acid synthesis, conjugation, and reabsorption.
Mean serum bile acid levels and pruritus at the end of the study were
Mean serum bile acid levels and pruritus at the end of the study were lower in both SHP625 and placebo treated groups as compared to baseline.
The drug, fexaramine, activates a protein called the farensoid X receptor (FXR) that plays a role in how the body releases bile acids from the liver, digests food and stores fats and sugars.
reuteri, they showed a significant increase in blood levels of free bile acid and significant decreases in the absorption of plant-derived cholesterol-like molecules.
Hypocholesterolemia of Rhizoma Coptidis alkaloids is related to the bile acid by up-regulated CYP7A1 in hyperlipidemic rats.
By selectively elevating BSH levels in conventionally raised mice with a normal microbiota, the study demonstrated BSH can modify plasma bile acid profiles which can influence pathways governing lipid metabolism, metabolic signalling events, circadian rhythm and immune function.
The binding of bile acid salts by CS stearate reduced the emulsion of fats in food, which thus inhibited the absorption of fats.
According to Burrin, the CDCA study is the first to demonstrate the use of small doses of this bile acid, delivered directly to the upper digestive tract, to control PNALD in a newborn-lab-animal model.
Bile acids are the major constituent of bile and the primary bile acids, cholic and chenodeoxycholic acid, and secondary bile acids, lithocholic and deoxycholic acid, make up more than 95% of the bile acid pool.