In food packaging, they have been replaced by shorter-chain fluorinated compounds that leave the body much more quickly and are less bioaccumulative
The matter was referred to the Committee by Germany under Article 35 of Directive 2001/82/EC, due to concerns that moxidectin may have persistent, bioaccumulative
and toxic (PBT) properties, and consequently a potential serious risk to the environment may arise from the use of products containing the substance.
The final assessment also concludes that four previously assessed substances were found not to be potentially persistent, bioaccumulative
and inherently toxic (PBiT).
MeHg is a bioaccumulative
neurotoxin, and that's important for several reasons.
, and Toxic (PBT) Chemicals: Technical Aspects, Policies, and Practices
Flame retardant chemicals such as HBCD (hexabromocyclododecane) and pentaBDE (pentabromodiphenyl ether) raise concerns for human health and the environment, including potential reproductive, developmental, and neurological effects and can be persistent, bioaccumulative
, and toxic to aquatic organisms.
ECHA said in a statement that the substances of initial concern relate to risks to human health or the environment for "potential persistent, bioaccumulative
, and toxic properties, suspected endocrine disruption or carcinogenic, mutagenic, and reprotoxic properties in combination with wide dispersive or consumer use.
An expert group has been set up by ECHA to help with the assessment of and validation of testing methods for chemicals suspected of being persistent, bioaccumulative
and toxic (PBT) or very persistent and very bioaccumula-tive (vPvB).
Mercury is a heavy metal, which is also persistent, bioaccumulative
and toxic (PBT) and can be spread over long distances.
HBCD is a persistent, bioaccumulative
and toxic (PBT) chemical, which has been labelled a "very worrying" substance under REACH criteria.
Short-chained chlorinated paraffins (SCCPs), used as lubricants and coolants for metal working and as plasticizers and flame retardants in plastics, are persistent, bioaccumulative
, and toxic to aquatic life.
Exposure to the persistent, bioaccumulative
flame retardant decabromodiphenyl ether (decaBDE) has been linked to developmental health effects, and the compound is scheduled to be phased out of production by December 2013.